try pytraj
online:
import warnings
warnings.filterwarnings('ignore', category=DeprecationWarning)
import pytraj as pt
from pytraj.plot import plot_matrix
traj = pt.iterload("tz2.nc", "tz2.parm7")
mat = pt.pairwise_rmsd(traj, '@CA')
mat
%matplotlib inline
%config InlineBackend.figure_format = 'retina'
import matplotlib
fig, asp, axi, = plot_matrix(mat)
fig.colorbar(axi, ax=asp)
# from matplotlib import pyplot as plt
# plt.savefig('plot_pairwise_rmsd.png')
(pairwise_rmsd.ipynb; pairwise_rmsd_evaluated.ipynb; pairwise_rmsd.py)